| Date |
25-5-2009 |
| Time |
10:30 |
| Room/Location |
DISI-Sala Conferenze 3° piano |
| Title |
Evolutionary Algorithms for Protein Ligand Docking |
| Speaker |
Prof. Susmita Ghosh |
| Affiliation |
Jadavpur University, Kolkata, India |
| Link |
https://www.disi.unige.it/index.php?eventsandseminars/seminars
|
| Abstract |
Protein-ligan docking is an important problem in bioinformatics and require
a lot of search space exploration.
The present work attempts to employ hybrid genetic algorithms (GAs) to solve
the flexible-ligand docking problem i.e. predicting the binding conformation
of a flexible ligand molecule into a rigid protein. Genetic algorithms are
reputed to perform good optimization and search. We used a genetic algorithm
to serach the space efficiently for this problem. Preliminary results
obtained on a set of three protein-ligand complexes are encouraging. |
